Bergonie & Tribondeau (1906) observations:

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    Bergonie & Tribondeau in 1906 developed a theory about radiation effects. They published the following:

  • Cells that are actively proliferating are the most sensitive to radiation.

  • The degree of differentiation of cells is inversely related to their radiosensitivity.

  • The radiosensitivity of cells is proportional to the duration of the mitotic and development activity.

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